As well as being an important interchange station, Crewe is home to a number of employers, including the Crewe Business Park, Caudwell Logistics, Bentley Motors and Manchester Metropolitan University. Crewe Alexandra FC is a 5 minute walk away, whilst the Crewe Heritage Centre, which is open on weekends from Easter to October, celebrates the towns rail heritage and is a 20 minute walk from the station. Rail passengers get a two for the price of one offer to the Heritage Centre with valid rail tickets.

One stop away from Crewe on the line to Shrewsbury is Nantwich, a pleasant market town, which regularly hosts farmers markets, food and drink events and music festivals.

Crewe has won two awards in the Cheshire Best Kept Station Competition.  In 2008, it won an award for its contribution to Cheshire's Year of Gardens.  In 2009, it won the Cheshire Customer Care Award.